Challenges in Managing an Ischemic Cerebral Vascular Stroke in a Child with a Homozygote SS Sickle Cell Associated with Cerebral Palsy: A Case Study

Authors

  • Muriel Amon Tanoh Félix Houphouët Boigny University, Abidjan, Republic of Côte d’Ivoire
  • Rosette Boundjike Félix Houphouët Boigny University, Abidjan, Republic of Côte d’Ivoire
  • Nancy Tanya De-Souza Félix Houphouët Boigny University, Abidjan, Republic of Côte d’Ivoire
  • Cedric Valery Kadjo Félix Houphouët Boigny University, Abidjan, Republic of Côte d’Ivoire
  • Mody Kone Félix Houphouët Boigny University, Abidjan, Republic of Côte d’Ivoire
  • Constance Yapo-Ehounoud Félix Houphouët Boigny University, Abidjan, Republic of Côte d’Ivoire
  • Ismaila Diakite Félix Houphouët Boigny University, Abidjan, Republic of Côte d’Ivoire
  • Christian Tanoh Félix Houphouët Boigny University, Abidjan, Republic of Côte d’Ivoire
  • Evelyne Aka Diarra Félix Houphouët Boigny University, Abidjan, Republic of Côte d’Ivoire
  • Berthe Assi Félix Houphouët Boigny University, Abidjan, Republic of Côte d’Ivoire

Keywords:

Stroke, Sickle cell anemia, Transfusion exchanges, Transcranial Doppler Ultrasound, Côte d’Ivoire

Abstract

Introduction: Ischemic stroke is one of the most frequently observed complications of sickle cell disease. It can also be associated with cognitive impairment. These two neurological expressions of the disease can coexist in the same patient. Objective: Report a case of stroke and mental retardation in a child with homozygous SS sickle cell disease. Observation: A child aged 5 years and 8 months, homozygous sickle cell anemia, epileptic noncompliant with his antiepileptic treatment, was admitted for epileptic seizures that gradually developed over 2 months. The diagnosis of severe complicated major sickle cell syndrome was established. Discussion: The management of neurovascular, epileptic, and cognitive complications of sickle cell disease in our patient with cerebral palsy and major sickle cell disease required evaluating the risk of occurrence of severe anemia and stratification of the risk of stroke recurrence. Conclusion: Management of a major sickle cell syndrome associated with neurovascular, epileptic, and cognitive impact in a child with sickle cell disease and cerebral palsy must comply with recent recommendations.

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Published

2024-11-22

How to Cite

Tanoh, M. A., Boundjike, R., De-Souza, N. T., Kadjo, C. V., Kone, M., Yapo-Ehounoud, C., … Assi, B. (2024). Challenges in Managing an Ischemic Cerebral Vascular Stroke in a Child with a Homozygote SS Sickle Cell Associated with Cerebral Palsy: A Case Study. ESI Preprints, 35, 96. Retrieved from https://esipreprints.org/index.php/esipreprints/article/view/1376

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Section

Preprints

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